Additionally, age, as a non-modifiable factor, also influences the autonomic nervous system regulation of the heart, with decreasing HRV during one’s lifespan.

Īs another example, lower HRV has been associated with poor prognosis in specific clinical conditions such as cardiovascular diseases, specifically risk stratification, and mortality prediction. Examples include biofeedback interventions in chronic disease management, the assessment of cognitive function, impairment and aging, psychological states in health and disease, including posttraumatic stress disorder or psychiatric disorders such as depression or anxiety, pain disorders, viral infections, as a prognostic factor for cancer survival, endurance exercise and training prescription, and the effect of exercise and training interventions in both resting states as well as during dynamic exercise and post-exercise recovery. Consequently, HRV possesses a broad range of applications in health and disease. This includes long-term mechanisms (e.g., circadian rhythms) and short-term processes integrating the autonomic, cardiovascular, and respiratory systems. In general, the variability in cardiac interbeat intervals is the result of the interaction of multiple regulatory mechanisms that operate at different time scales. The biosignal of heart rate (HR) variability (HRV) signifying cardiac interbeat interval variation is a promising candidate as a non-invasive marker for the exploration of cardiac autonomic function, with applications both in remote, local laboratory, and clinical settings.

The Movesense Medical device can be used in lieu of a reference ECG for the calculation of HRV with the potential to differentiate noise from atrial fibrillation and represents a significant advance in both a HR and HRV recording device in a chest belt form factor for lab-based or remote field-application. Bland–Altman analysis showed high agreement between devices (PRE and POST: meanRR bias of 0.0 and 0.4 ms, LOA of 1.9 to −1.8 ms and 2.3 to −1.5 EX: meanRR bias of 11.2 to 6.0 ms LOA of 29.8 to −7.4 ms during low intensity exercise and 8.5 to 3.5 ms during high intensity exercise). There was no significant difference in device specific meanRR during PRE and POST. Results showed excellent correlations between devices for linear indexes with Pearson’s r between 0.98 to 1.0 for meanRR, SDNN, RMSSD, and 0.95 to 0.97 for the non-linear index DFA a1 during PRE, EX, and POST. A heterogeneous group of 21 participants performed an incremental cycling ramp to failure with measurements of HRV, before (PRE), during (EX), and after (POST). The intent of this report is to validate a new single channel ECG device, the Movesense Medical sensor, against a conventional 12 channel ECG.

The typical mobile-based HRV device simply records interbeat intervals, without differentiation between noise or arrythmia as can be done with an electrocardiogram (ECG). The value of heart rate variability (HRV) in the fields of health, disease, and exercise science has been established through numerous investigations.

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